CAC2 Childhood Cancer Community News Digest (December 4-10)

December 11, 2023 Community News, News Digest

Assorted News from the Last Week:

CAC2 Members Nicole Scobie (Zoe4Life) and Nick Bird (Solving Kids’ Cancer-UK) contributed to this Journal of Clinical Oncology commentary calling for a new regulatory approach for developing CAR-T therapies for pediatric cancer patients.

CAC2 Members, Focused Ultrasound Foundation and Arms Wide Open Childhood Cancer Foundation (AWOCCF) are pleased to announce their first collaborative initiative to fund a research project exploring the role of noninvasive focused ultrasound in treating high-risk pediatric neuroblastoma.

BrainChild Bio, a newly-launched spinout of Seattle Children’s Hospital focused on childhood central nervous system cancers launches and rather than starting with regulatory approval for its drugs in adults, the company will aim for a greenlight for pediatric patients first.

What comes after NCI-MATCH? NCI’s new precision medicine cancer trials

Replacing brentuximab vedotin with nivolumab in first-line treatment combined with the chemotherapy regimen AVD improved progression-free survival in pediatric patients with newly diagnosed, advanced-stage classic Hodgkin lymphoma (cHL).

A review of CNS tumors common in adolescents and young adults

Using pharmacogenomics to guide induction may reduce racial disparities in pediatric AML

Upcoming Webinars, Online Opportunities, and Meetings:

ALADDIN Webinar: Overview of early phase drug development in pediatric oncology:  An educational program on strategic and regulatory science in pediatric oncology drug development on December 14, at 11:00 ET.  For information and to register.

Free webinar hosted by NCI:  “Navigating St. Jude’s PeCan v2 & Survivorship Data Sharing Tools” on January 23 at 1:00–2:00 p.m. ET.  Register here.

ACCELERATE Annual Conference 2024 on February 8 & 9 in Brussels). Learn about the most recent successes in paediatric oncology drug development worldwide, the latest regulatory updates in Europe and North America and more.  For information and to register.

Austin Hatcher Foundation Bubbles of Fun 5K, 10K, and 1-Mile Fun Run, February 10 at Tennessee Riverpark.  For information and to register.

Alliance for Childhood Cancer has announce that Action Days 2024 will take place in Washington, DC from February 13-14, 2024. Registration will open in mid-December.  Click for information.

FDA’s Rare Disease Day will be on Friday, March 1, 2024, and registration is open for this virtual event. This year’s Rare Disease Day is dedicated to patients and health care professionals.

Recent Recordings:

CAC2 member Mark Levine hosts a podcast called, “Help and Hope Happen Here” (available on Apple Podcasts, Spotify, and Google Podcasts). Access recent podcasts with CAC2 Members (and visit Help and Hope Happen Here for interviews with other CAC2 members and thought leaders from around the community):

Trabectedin plus low-dose irinotecan promising in Ewing sarcoma

Take Action:

Wanted: 100 cosponsors for the Give Kids a Chance Act (S 2897, HR 3433) before Christmas!  Kids v Cancer is seeking pediatric cancer organizations to host zooms for their kids (ages elementary school to young adult) to talk to Congressional offices.  Make this your holiday event, or sign up as an individual kid!   We will provide training and zooms.  No experience necessary.  Please contact: .  See also: https://www.givekidsachanceact.org/be-the-voice-of-childhood-cancer.

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