CAC2 Childhood Cancer Community News Digest (November 27-December 3)

Assorted News from the Last Week:

Dr. Andy Kolb of CAC2 Member Leukemia & Lymphoma Society explains why a well-meaning FDA policy is a threat to pediatric cancer treatment.

Pediatric cancer survivors treated with abdominopelvic region radiotherapy (ART) have an increased risk of colorectal cancer (CRC), according to research published in the Journal of Clinical Oncology.

CAR-T therapy was first approved in November 2017 for life-threatening blood cancers. But recently, the F.D.A. said, it had received 19 reports of new blood cancers in patients who received the treatment.

ASCO issues clinical guidance for alternative treatments during oncology drug shortages

Scientists at the Princess Máxima Center for pediatric oncology and the Hubrecht Institute have developed mini-organs with features like cell organization, stem cell expansion and cell identity that more closely mimic the real-life situation. These novel organoids can be used as a basis to model pediatric brain tumors.

Children’s Hospital of Los Angeles introduces four innovations that improve pediatric radiation therapy.

Upcoming Webinars, Online Opportunities, and Meetings:

ALADDIN Webinar: Overview of early phase drug development in pediatric oncology:  An educational program on strategic and regulatory science in pediatric oncology drug development on December 14, at 11:00 ET.  For information and to register.

Free webinar hosted by NCI:  “Navigating St. Jude’s PeCan v2 & Survivorship Data Sharing Tools” on January 23 at 1:00–2:00 p.m. ET.  Register here.

ACCELERATE Annual Conference 2024 on February 8 & 9 in Brussels). Learn about the most recent successes in paediatric oncology drug development worldwide, the latest regulatory updates in Europe and North America and more.  For information and to register.

Austin Hatcher Foundation Bubbles of Fun 5K, 10K, and 1-Mile Fun Run, February 10 at Tennessee Riverpark.  For information and to register.

Recent Recordings:

CAC2 member Mark Levine hosts a podcast called, “Help and Hope Happen Here” (available on Apple Podcasts, Spotify, and Google Podcasts). Access recent podcasts with CAC2 Members (and visit Help and Hope Happen Here for interviews with other CAC2 members and thought leaders from around the community):

Take Action:

Wanted: 100 cosponsors for the Give Kids a Chance Act (S 2897, HR 3433) before Christmas!  Kids v Cancer is seeking pediatric cancer organizations to host zooms for their kids (ages elementary school to young adult) to talk to Congressional offices.  Make this your holiday event, or sign up as an individual kid!   We will provide training and zooms.  No experience necessary.  Please contact: .  See also:

NCI is seeking input through a request for information about the CCDI Data Ecosystem. Fill out this survey to tell us how you use the CCDI Data Ecosystem, what types of childhood cancer data would advance your work, and what barriers you encounter when using and accessing data from the ecosystem. Responses are due November 30.


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