All posts tagged: Research

CC Community News Digest (October 5-11)

Assorted news from the last week: Researchers at Baylor College of Medicine and the University of North Carolina at Chapel Hill have genetically modified human NKT cells with a chimeric antigen receptor (CAR) that enables them to specifically recognize and attack neuroblastoma, a form of childhood cancer. In a recent Journal of Clinical Oncology article, members from the US Food and Drug Administration (FDA) and European Medicines Agency (EMA) expressed the need for trial sponsors to coordinate their submissions of initial pediatric study plans (iPSP) and pediatric investigation plans (PIP) with regulatory authorities in order to facilitate pediatric cancer drug […]

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CC Community News Digest (week of September 28-October 4)

Assorted news from the last week: Twenty percent of children treated with drugs called anthracyclines go on to suffer heart failure later in life.  Dr. Greg Aune explores why. Research to develop a new treatment and bring a new drug to market is extremely expensive, and conventional methods for obtaining funding aren’t adequate. New funding models can help disease-focused nonprofit research foundations play a central role in raising capital and mobilizing an ecosystem focused on controlling and curing a disease. The U.S. Senate unanimously passed S.Res.742 – A Senate Resolution designating September as National Childhood Cancer Awareness Month.  Senators Manchin […]

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CC Community News Digest (week of September 21-27)

Assorted news from the last week: In a Swedish study of how families in pediatric oncology experienced illness‐related information and communication with professionals and within the family, eighty‐six percent of the parents and 71% of the siblings reported that they had not received enough or any information about how the cancer and its treatment could affect the child's psychological health. EMA has published the final version of ‘Preparedness of medicines’ clinical trials in paediatrics - recommendations by the Enpr-EMA working group on trial preparedness.'  Key takeaways:  The definition of “trial preparedness” has been extended and a new term “trial feasibility” has [...] Read more

CC Community News Digest (week of September 14-20)

Assorted news from the last week: A study by a French research team found “that treatment with growth hormones is not associated with an increased risk of second tumors” for children who survived cancer and later received treatment for growth hormone deficiency. Brigitte Widemann, chief of the Pediatric Oncology Branch for the Center for Cancer Research at the National Cancer Institute, started conducting clinical trials for neurofibromatosis type 1 (NF1) in 2001, and results from the most recent trial holds promise to shrink the tumors or stop their growth. FDA grants rare pediatric disease designation to a second CAR (chimeric [...] Read more

CC Community News Digest (week of September 7-13)

Assorted news from the last week: Camp Okizu at Berry Creek, a camp for pediatric cancer patients and their families, sustained significant damage in California's Bear Fire. Early results of a clinical trial show that for children and adults with advanced soft tissue sarcoma, adding the targeted drug pazopanib (Votrient) to chemotherapy and radiation treatment is safe and increases the chances that most of the tumor will be dead before surgery. Study in Pediatric Blood Cancer concludes that physicians can foster trust through patient-centered communication and provision of high-quality information about a child’s cancer. Baltimore Ravens honor pediatric cancer patients. [...] Read more

CC Community News Digest (week of August 31-September 6)

Assorted news from the last week: National Cancer Institute released its Annual Plan and Budget Proposal for Fiscal Year 2022.  This plan focuses on our enduring top priority — accelerating cancer research — and features four special scientific topics: cancer drug resistance, molecular diagnostics for cancer treatment, obesity and cancer, and cancer survivorship. Major League Soccer and Continental Tire teamed to raise awareness and funds for childhood cancer with the 7th year of the Kick Childhood Cancer campaign. Major League Baseball devoted Saturday, September 5 to childhood cancer activities around the league.  Players wore gold ribbon decals and wristbands, and teams [...] Read more

CC Community News Digest (week of August 24-30)

Assorted news from the last week: Cancer and its treatment may accelerate the aging process in young patients Research has identified a small molecule compound that may make some medulloblastoma patients respond better to treatment Childhood Cancer virtual Action Day planned for September 9 Chadwick Boseman, who died of cancer Friday at age 43, inspired many in roles as King T'Challa, Jackie Robinson and James Brown, but also used his prominence to lift up children with cancer. CAC2 salutes Members Solving Kids’ Cancer, Momcology, Ty Louis Campbell Foundation, and the Max Cure Foundation who worked collaboratively with Friends of Karen [...] Read more

International Society of Pediatric Oncology (SIOP) Moves Congress Online

On behalf of the International Society of Paediatric Oncology (SIOP), please note that SIOP 2020 will take place as a virtual congress on the same dates: October 14-17, 2020.  Additionally, Late-Breaking Abstract Submission is open until August 26, allowing everyone to share their research from wherever they are based.   SIOP 2020 Virtual Congress October 14-17, 2020   In light of the continuing uncertainty about the evolution of the COVID-19 pandemic, we have decided to transform SIOP 2020 into a virtual congress, taking place on the same dates: October 14-17, 2020. With updated registration rates starting from EUR 25, […]

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Phase III Pediatric Brain Tumor Clinical Trial Collaboration

Everybody is worried these days.  We have witnessed toilet paper hoarding and other behaviors that make us feel vulnerable and alone.  That's why we would like to hold up and highlight some fabulous Member Collaborations.   One recent collaboration between two CAC2 members really brings this story of hope in the midst of worry during Coronavirus as these two organizations, The Taylor Matthews Foundation and the Pediatric Brain Tumor Foundation found a way to support funding for a Phase III clinical trial. Here's the story in their words: "As you may recall, The Taylor Matthews Foundation first linked arms with PBTF [...] Read more

Cancer in Children with Birth Defects: What Can We Learn from Population-Based Studies 

Our April CAC2 All-Member webinar hosted by Donna Ludwinski (Solving Kids Cancer) introduced Drs. Jeremy Schraw and Philip Lupo of Baylor College of Medicine who spoke about their research on nonchromosomal cancer predisposition. Studies show that birth defects are one of the strongest risk factors for cancer in children, but who is at risk and why? To address these questions, the presenters performed the largest investigation of cancer risk in children with birth defects to date. They discussed how a child’s risk of cancer relates to the type and number of birth defects they are diagnosed with, evidence for possible genetic and [...] Read more